Journal of Research in Ayurvedic Sciences

Register      Login

VOLUME 2 , ISSUE 4 ( October-December, 2018 ) > List of Articles

RESEARCH ARTICLE

Role of Shodhana with Haritakyadi Yoga in Increasing Sperm Count in the Case of Oligozoospermia: An Open-labeled Clinical Trial

Mandip R Goyal, Anup B Thakar, Shilpa B Donga, Divyarani Kathad

Keywords : Haritakyadi yoga, Shodhana, Vajikarana., Oligozoospermia, Total sperm count,Ayurveda

Citation Information : Goyal MR, Thakar AB, Donga SB, Kathad D. Role of Shodhana with Haritakyadi Yoga in Increasing Sperm Count in the Case of Oligozoospermia: An Open-labeled Clinical Trial. J Res Ayurvedic Sci 2018; 2 (4):233-239.

DOI: 10.5005/jp-journals-10064-0063

License: CC BY-NC 4.0

Published Online: 00-12-2018

Copyright Statement:  Copyright © 2018; Jaypee Brothers Medical Publishers (P) Ltd.


Abstract

Aim and objectives: Infertility is often defined as the inability to conceive after 12 months of regular sexual intercourse without the use of birth control. Around 10% of women aged 25–44 years are estimated to have difficulty conceiving or staying pregnant. Worldwide, 8–12% of couples experience fertility problems. Between 45% and 50% of cases are thought to stem from factors that affect men. Oligozoospermia refers to semen with a low concentration of sperm and is a common finding in male infertility. Hence, the present clinical trial was planned to assess the role of Shodhana (biocleansing) performed by Haritakyadi Yoga in increasing the sperm count in the case of oligozoospermia. Vajikarana therapy improves the nourishment and function of the reproductive organs and vitalizes tissues of the reproductive organs, increasing semen potency specially administered after Shodhana (biocleansing). Haritakyadi Yoga is mentioned in the Rasayana chapter of Charaka Samhita for the purpose of Shodhana (biocleansing) before administration of Rasayana and Vajikarana (aphrodisiac) drugs. Materials and methods: For the clinical study, 93 male patients suffering from primary or secondary infertility for more than one year and having sperm count less than 15 million/mL were selected irrespective of religion and caste. The effect of the therapy was assessed by the status of seminal parameters before and after the Shodhana procedure. Results and discussion: Performing Shodhana (biocleansing) with Haritakyadi Yoga induced Vamana (emesis) and Virechana (purgation) with a moderate type of Shuddhi in a maximum number of treated patients. It also provided a statistically significant increase in the total sperm count (71.24%), sperm motility (16.82%), semen volume (47.14 mL), serum luteinizing hormone (LH) (19.84%), serum follicle stimulating hormone (FSH) (33.09%), and serum testosterone (20.56%). Conclusion: Results of the present clinical trial indicates that performing Shodhana (biocleansing) with the Haritakyadi Yoga procedure is effective in the case of oligozoospermia.


PDF Share
  1. http://www.charaka.org/oligospermia-low-sperm-count/, accessed date: 17/1/2019, 2.50pm
  2. http://www.charaka.org/oligospermia-low-sperm-count/, accessed date: 17/1/2019, 2.50pm
  3. https://academic.oup.com/humupd/article/10/4/317/635694, accessed date: 21/12/2017, 3.45pm
  4. Pandit Hemaraj Sharma Vriddha Jivaka Tantra, Kashyapa Samhita, Vidhotin commentary, Pandit Hemaraj Sharma. Chaukhmbha Sanskrita Sansthan, Varanasi. edited reprinted 2013. Sutra Sthana Adhyaya-2, p.7.
  5. Jitendra Varsakiya et al. Role of virechana karma in increasing sperm count in the case of oligozoospermia: an open labelled clinical trial. Int J Res Ayurveda Pharm 2017;8(Suppl 2):134138 http://dx.doi.org/10.7897/2277-4343.08298
  6. http://www.who.int/rpc/research_ethics/pdf, accessed date: 11/1/2019, 9:00pm
  7. WHO Crieteria for normal semenogram 2010. Impact of the new WHO Guidelines on diagnosis and practice on male infertility, Open Reprod Sci J 2010;3:7-15.
  8. Cooper TG, Noonan E, von Eckardstein S, Auger J, Baker HW, Behre HM, Haugen TB, Kruger T, Wang C, Mbizvo MT, Vogelsong KM. “World Health Organization reference values for human semen characteristics” (PDF). Hum Reprod Update May–Jun 2010;16(3):23145. doi: 10.1093/humupd/dmp048. PMID 19934213.
  9. Aacharya YT, editor. Charaka Samhita of Agnivesha, Siddhi Sthana. Reprint ed. Ch. 2/11, Ver. 61. Varanasi: Chaukhamba Surbharati Prakashan; 2008. p.688.
  10. Aacharya YT, editor. Charaka Samhita of Agnivesha, Sutra Sthana. Reprint ed. Ch. 13, Ver. 61. Varanasi: Chaukhamba Surbharati Prakashan; 2008. p.85.
  11. Aacharya YT, editor. Charaka Samhita of Agnivesha, Sutra Sthana. Reprint ed. Ch. 1, Ver. 10. Varanasi: Chaukhamba Surbharati Prakashan; 2008. p.678.
  12. Aacharya YT, editor. Charaka Samhita of Agnivesha, Sutra Sthana. Reprint ed. Ch. 1, Ver. 11. Varanasi: Chaukhamba Surbharati Prakashan; 2008. p.678.
  13. Aacharya YT, editor. Charaka Samhita of Agnivesha, Chikitsa Sthana ch 7/120. Reprint ed. Ch Varanasi: Chaukhamba Surbharati Prakashan; 2008. p.456.
  14. Mehra BL., Studies on Klaibya (male sexual dysfunction) and its management with V j karana, Jamnagar: Department of Kayachikitasa, I.P.G.T. & R.A., G.A.U.; 1996.
  15. Mohammad Eid hammadeh et al. Reactive Oxygen Species and Antioxident in Seminal Plasma and Their Impact On Male Infertility IJFS Nov-Dec 2009;3(3):87-110.
  16. Agnivesha, Charaka, Dradhabala, Charakasamhita, Vidhyotini Hindi commentary, Sutra sthana Ch. 16/17-18; 315, Narayana Shashtri, editor. Varanasi: Chaukhambha Bharati Academy; 2013.
  17. Agnivesha, Charaka, Dradhabala, Charakasamhita, Vidhyotini Hindi commentary, Siddhisthana Ch. 2/13; 981, Narayana Shashtri, editor. Varanasi: Chaukhambha Bharati Academy; 2013.
  18. Agnivesha, Charaka, Dradhabala, Charakasamhita, Vidhyotini Hindi commentary, Siddhi Sthana, Ch. 2/6;225, Narayana Shashtri, editor. Varanasi: Chaukhambha Bharati Academy; 2013. p.860-861.
  19. Vd. Jadavaji Trikamaji Acharya, Agnivesha ‘Charaka Samhita’, revised by Charaka and Dridhabala with ‘Ayurveda Deepika’ commentary by Chakrapanidatta, Varanasi-221 001, (India), reprint 2008, Chikitsa Sthana, Adhyaya-1/8: Chaukhambha Surabharati Publications. p.304.
  20. Bhavamishra, commentatoer, Chunekar KC, Bhavaprakaash Nighantu, Chaukhmabha Bharatiya Prakashan Varanasi, 2010, purvakhanda 1/16-17, p.398.
  21. Bhavamishra, commentatoer, Chunekar KC, Bhavaprakaash Nighantu, Chaukhmabha Bharatiya Prakashan Varanasi, 2010 purvakhanda 1/57, p.403.
  22. Iranloye BO, Oludare GO, Morakinyo AO, Esume NA, Ekeh LC. Reproductive parameters and oxidative stress status of male rats fed with low and high salt diet, J Hum Reprod Sci. 2013 Oct-Dec;6(4):267-272. doi: 10.4103/ 0974-1208.126308.
PDF Share